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Coronavirus (COVID-19) Clinical Guidance Repository
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Last Updated January 14, 2021.
The AAMC Coronavirus (COVID-19) Clinical Guidance Repository is an open access resource for all clinicians and hospitals across the United States. The content is collected from academic medical centers (AMCs), specialty societies, and federal partners. The goal is to identify, summarize, and highlight areas of alignment in clinical practice during the pandemic.
Here you will find up to date COVID-19 treatment and management guidance to help clinicians optimize patient care. For some topics clinical alignment guidance summarizes areas of agreement across several institutions and/ or organizations. Clinicians can view, access, and download the materials.
This repository is meant only for clinicians (not the general public) to access clinical and patient management information regarding COVID-19 that supplements their own independent, professional judgment, and evaluation of their institution’s unique circumstances (AAMC Coronavirus (COVID-19) Clinical Guidance Repository Disclaimer).
After reviewing the repository, AAMC would appreciate your feedback on the usefulness of this resource. Please send your feedback to AAMC via email.
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Submit COVID-19 Clinical Guidance
The AAMC will consider additional materials for the Coronavirus (COVID-19) Clinical Guidance Repository. While the repository is publicly available, only AAMC member institutions, affiliated organizations and societies, and federal partners can submit clinical guidance to be displayed on this site. By submitting clinical guidance, you agree to the following terms and conditions (AAMC Coronavirus (COVID-19) Clinical Guidance Repository Submission Terms).
As of November 25, 2020, new guidance on Crisis Standards of Care have been added. Many hospitals across the United States are experiencing large surges in COVID-19 patients and intensive care units are already over capacity in many areas. There may come a point in the crisis at which all the contingent surge adaptations cannot compensate for the overwhelming caseload and decisions must be made to do the most good with limited resources. At that point, clinicians and hospitals shift from conventional to crisis standards of care (CSC). Guidance on CSC below:
National Academies of Sciences, Engineering, and Medicine
- Crisis Standards of Care: A Systems Framework for Catastrophic Disaster Response (Volume 1): Cross-Cutting Themes
- Background and key elements of CSC.
- Provides guidance on determining core values that affect allocation decisions (e.g., fairness, duty to care, duty to steward resources, transparency, consistency, proportionality, accountability)
- Provides guidance on engaging families and palliative care departments in end-of-life discussions (pages 1-78 to 1-86)
- Crisis Standards of Care: A Systems Framework for Catastrophic Disaster Response (Volume 4): Hospitals and Acute Care Facilities
- Provides guidance on optimizing communication and ensuring that clinicians know what support is available for their decisions under CSC
- Hospital and Acute Care Toolkit
- Rapid Expert Consultation on Staffing Considerations for Crisis Standards of Care for the COVID-19 Pandemic
- Provides guidance on understanding the key principles of CSC and informing and engaging hospital and health system personnel in CSC planning
Additional Crisis Standards of Care Resources and Perspectives
-
Association of American Medical Colleges (AAMC):
- Health and Human Services (HHS) Assistant Secretary for Preparedness and Response (ASPR), the Technical Resources, Assistance Center, and Information Exchange (TRACIE)
- The Johns Hopkins Center for Health Security
- New England Journal of Medicine
- Journal of the American Medical Association
- The American College of Chest Physicians Task Force on Mass Critical Care
The following summaries describe how clinical guidance from different organizations are aligned on each topic area.
- COVID-19 Infectious Disease Treatment (12/18/20)
- COVID-19 Isolation Precautions (12/30/20)
- COVID-19 Critical Care Management (12/30/20)
- COVID-19 Discharge Guidance (12/30/20)
- In-Person and Remote Ambulatory Care Guidance for COVID-19 (6/30/20)
- Veno-venous Extracorporeal Membrane Oxygenation (ECMO) (1/11/21)
American Heart Association and Partners
Interim Guidance for Basic and Advanced Life Support in Adults, Children, and Neonates With Suspected or Confirmed COVID-19
Infectious Diseases Society of America
Infection Prevention in Patients with Suspected or Known COVID-19
Johns Hopkins Medicine
Johns Hopkins Medicine COVID-19 Environmental Cleaning, Waste and Linen Guidance
Johns Hopkins Medicine COVID-19 Inpatient Personal Protective Equipment (PPE) Guidance
Johns Hopkins Medicine COVID-19 Airborne and Contact Precautions with Eye Protection
Johns Hopkins Medicine Isolation Precaution Discontinuation and Re-testing Guidance
Johns Hopkins Medicine Removal of COVID-19 Isolation Precautions for Ambulatory Patients
Massachusetts General Hospital
Massachusetts General Hospital Guidance for Patients with Suspected Viral Respiratory Illness
Massachusetts General Hospital Patients with Confirmed COVID-19: Criteria for Resolution of COVID-19 Infection Status and Discontinuation of Isolation
University of California at San Francisco
UCSF Inpatient, ED and OB Guidelines for Symptomatic and Asymptomatic Patients
UCSF Discontinuing Isolation for Patients with COVID-19
UCSF Health Guidance for Discontinuing Isolation for Severely Immunocompromised COVID+ Patients
Johns Hopkins Medicine
Johns Hopkins Medicine COVID-19 Testing Algorithm for the Adult Emergency Department
University of Washington Medicine
University of Washington Emergency Department COVID-19 Airway Policies
University of Washington Emergency Department Risk Assessment
Massachusetts General Hospital
Massachusetts General Hospital Prone Positioning Protocol for Non-Intubated Patients
National Institutes of Health
NIH Coronavirus Disease 2019 (COVID-19) Treatment Guidelines
University of California San Francisco
UCSF Adult COVID-19 Management Guidelines
University of Washington Medicine
University of Washington High-Flow Nasal Cannula in the Management of Patients with COVID-19
Discharge Guidance
Johns Hopkins Medicine
Johns Hopkins Medicine Discharge Guidelines for COVID-19 Positive Patients Still on COVID-19 Isolation
Johns Hopkins Medicine Discharge Guidance for Patients with Severe Illness
University of Washington Medicine
University of Washington Discharge Home Checklist for Hospitalized Patients with COVID-19
Addiction Medicine Treatment Guidance
American Society of Addiction Medicine
Addiction Treatment in Hospital Settings During the COVID-19 Crisis
Infectious Diseases Treatment Guidance
Infectious Diseases Society of America
IDSA Guidelines on the Treatment and Management of Patients with COVID-19
Massachusetts General Hospital
Massachusetts General Hospital COVID-19 Treatment Guidance
National Institutes of Health
NIH COVID-19 Treatment Guidelines: Potential Antiviral Drugs Under Evaluation for the Treatment of COVID-19
NIH COVID-19 Treatment Guidelines: Immune-Based Therapy Under Evaluation for Treatment of COVID-19
NIH COVID-19 Treatment Guidelines Panel’s Statement on the Emergency Use Authorization of Convalescent Plasma for the Treatment of COVID-19
NIH COVID-19 Treatment Guidelines: Considerations for Certain Concomitant Medications in Patients with COVID-19
NIH COVID-19 Treatment Guidelines: Statement on the Emergency Use Authorization of Bamlanivimab for the Treatment of COVID-19
NIH COVID-19 Treatment Guidelines: Statement on Emergency Use Authorization of Casirivimab Plus Imdevimab Combination
NIH COVID-19 Treatment Guidelines: Statement on Emergency Use Authorization of Baricitinib
University of Washington Medicine
University of Washington COVID-19 Treatment Guidelines
Cardiology Guidance
American College of Cardiology
Management of the Hospitalized COVID-19 Patient With Acute Cardiomyopathy or Heart Failure
European Society of Cardiology
ESC Guidance for the Diagnosis and Management of CV Disease During the COVID-19 Pandemic
Critical Care Guidance
Emory Healthcare
Emory Healthcare Guidelines for the Care of Critically Ill Patients with COVID-19
Emory Healthcare Overview of the Management of Patients with COVID-19 For Non-Critical Care Providers
Massachusetts General Hospital
Massachusetts General Hospital Treatment Guidance for Critically Ill Patients with COVID-19
Massachusetts General Hospital Prone Positioning Protocol for Intubated Patients
Massachusetts General Hospital High Flow Nasal Cannula (HFNC) Use in Patients with COVID-19 ARDS
National Institutes of Health
NIH COVID-19 Treatment Guidelines: Care of Critically Ill Patients with COVID-19
Society for Critical Care Medicine
Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19)
Combined Recommendation Tables
Summary of Recommendations on the Initial Management of Hypoxic COVID-19 Patients
Summary of Recommendations on the Management of Patients with COVID-19 and ARDS
University of Washington Medicine
University of Washington Medicine Critical Care Management of COVID-19
Prevention and Treatment of Venous Thromboembolism (VTE)
Emory Healthcare
Emory Healthcare Guidelines for the Prevention and Treatment of VTE in Critically Ill Patients with COVID-19
Emory Healthcare VTE and Prophylaxis Guidelines for COVID-19 in the ICU—Summary
Massachusetts General Hospital
Massachusetts General Hospital Hematology Issues during COVID-19
National Institutes of Health
NIH COVID-19 Treatment Guidelines: Antithrombotic Therapy in Patients with COVID-19
Acute Renal Replacement Therapy (RRT)
American Society of Nephrology
Recommendations on the Care of Hospitalized Patients with COVID-19 and Kidney Failure Requiring Renal Replacement Therapy
Emory Healthcare
Emory Healthcare Guidelines for Acute RRT For Critically Ill Patients in ICU Settings During Respiratory Pandemic
Emory Healthcare Renal Replacement Therapy Surge Plan
Emory Healthcare Quick Reference – Improving CRRT Circuit Performance (COVID+ Patients)
Extracorporeal Membrane Oxygenation (ECMO)
Massachusetts General Hospital
Massachusetts General Hospital COVID-19 ECMO Protocol
National Institutes of Health
NIH COVID-19 Treatment Guidelines: Extracorporeal Membrane Oxygenation
University of Washington Medicine
University of Washington ECMO Support for Patients with COVID-19
Tracheostomy
American Academy of Otolaryngology-Head and Neck Surgery
Tracheotomy Recommendations During the COVID-19 Pandemic
Brain Death Determination
Emory Healthcare
Brain Death Testing in the Setting of COVID-19
Johns Hopkins Medicine
Johns Hopkins Medicine COVID-19 Testing Algorithm for Pediatric and Adult Ambulatory Clinics
Johns Hopkins Medicine Outpatient Office Guidelines for COVID-19
Massachusetts General Hospital
Massachusetts General Hospital Patient Flow through Respiratory Illness Clinic and Primary Care Patient Flow
University of California, San Francisco
UCSF COVID-19 Hotline and MyChart Adult Triage Protocol
UCSF Health COVID-19 Ambulatory Adult Remote Triage
UCSF Health COVID-19 Algorithm for On-Site Respiratory Evaluation in Adult Respiratory Screening Clinics
University of Washington Medicine
University of Washington COVID-19 Workflow for Ambulatory Settings
Ariadne Labs (Brigham and Women’s Hospital and Harvard T.H. Chan School of Public Health)
Ariadne Labs Serious Illness Care Program COVID-19 Response Toolkit
Massachusetts General Hospital
Massachusetts General Hospital Basic Guide for Serious Illness Discussion
Massachusetts General Hospital Talking about CPR with Very Sick Patients
Massachusetts General Hospital Symptom Management in Comfort-Focused Care Plan
Massachusetts General Hospital Opioid Decision Tree for Treatment of Dyspnea
Massachusetts General Hospital
Massachusetts General Hospital Guide to Mental Health Resources for COVID-19
Chronic Pain
American Academy of Pain Medicine and Partners
Pain Management Best Practices from Multispecialty Organizations during the COVID-19 Pandemic and Public Health Crises
American Society of Regional Anesthesia and Pain Medicine and European Society of Regional Anesthesia and Pain Therapy
Recommendations on Chronic Pain Practice during the COVID-19 Pandemic
Immunosuppressed
University of Washington Medicine
University of Washington Immunosuppressed Patient COVID-19 and Respiratory Viral Testing Guidelines
Influenza and COVID-19
National Institutes of Health
NIH COVID-19 Treatment Guidelines: Influenza and COVID-19
Obstetrics
American College of Obstetricians and Gynecologists
Outpatient Assessment and Management for Pregnant Women with Suspected or Confirmed Novel Coronavirus (COVID-19)
Massachusetts General Hospital
Massachusetts General Hospital Treatment Guide for Critically Ill Pregnant Patients
National Institutes of Health
NIH COVID-19 Treatment Guidelines: Special Considerations in Pregnancy and Post-Delivery
Society for Maternal-Fetal Medicine and Society for Obstetric and Anesthesia and Perinatology
Labor and Delivery COVID-19 Considerations
Management Considerations for Pregnant Patients with COVID-19
University of California San Francisco
UCSF Health COVID-19 Ambulatory Remote Triage for OB Patients with Respiratory Symptoms
Pediatrics
American Academy of Pediatrics
Management of Infants Born to Mothers with COVID-19
Guidance on Newborn Screening During COVID-19
Breastfeeding Guidance Post Hospital Discharge for Mothers or Infants with Suspected or Confirmed SARS-Co V-2 Infection
Family Presence Policies for Pediatric Inpatient Settings During the COVID-19 Pandemic
Guidance on Providing Pediatric Well-Care During COVID-19
Multisystem Inflammatory Syndrome in Children (MIS-C) Interim Guidance
COVID-19 Interim Guidance: Return to Sports
Johns Hopkins Medicine
Johns Hopkins Medicine Multisystem Inflammatory Syndrome in Children: Ambulatory Triage Algorithm
Johns Hopkins Medicine Multisystem Inflammatory Syndrome in Children: Pediatric Emergency Department
National Institutes of Health
NIH COVID-19 Treatment Guidelines: Special Considerations in Children
University of California San Francisco
UCSF COVID-19 Pediatric Clinical Evaluation Guide
UCSF Pediatric Caretaker and Patient Guidance in the ED and Inpatient Setting
University of Washington Medicine
University of Washington Newborn Nursery COVID-19 Guidance
Rheumatology
American College of Rheumatology
COVID-19 Clinical Guidance for Adult Patients with Rheumatic Diseases
U.S. Department of Health and Human Services Office of the Assistant Secretary for Preparedness and Response
HHS/ASPR COVID-19 Clinical Rounds