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Comparative Effectiveness and Outcomes Research

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To make informed care decisions, clinicians and patients need to compare and evaluate various treatment options. Comparative effectiveness research happening at AAMC member institutions supports this decision-making by enhancing the clinical information available about health interventions and care outcomes.   

Through our work, the AAMC promotes both research and dissemination strategies for studying effective treatments and sharing evidence-based practices. Additionally, the AAMC supports efforts of federal government agencies and other organizations to advance knowledge and engagement in these areas.

The Latest News 

Generating Real-World Evidence to Enhance Knowledge during COVID-19

As the scientific research community responds to COVID-19, there is value in using real-world data and evidence to inform clinical research. The AAMC’s Research on Care Community (ROCC) hosted a webinar featuring Lesley H. Curtis, PhD, Professor and Chair of the Department of Population Health Sciences at Duke University School of Medicine, who discussed the benefits as well as challenges of generating real-world evidence and highlight specific examples related to COVID-19 research.
View Recording | Download Slides

Communications and Insights 

More medical research = better patient care
AAMC Chief Public Policy Officer, Karen Fisher, JD, and Chief Scientific Officer, Ross McKinney Jr., MD, describe the importance of sustained biomedical research investment through the National Institutes of Health (NIH) and continued funding for comparative effectiveness research through the Patient-Centered Outcomes Research Institute (PCORI).

AAMC Statement on Next PCORI Executive Director, Nakela Cook, MD
AAMC Chief Scientific Officer, Ross McKinney Jr., MD, issued the following statement congratulating Dr. Cook on her appointment as the new Executive Director of the Patient-Centered Outcomes Research Institute (PCORI).

How do you know what treatment is right for you . . . or your patients?
This AAMCNews article, describes the importance of patient-centered outcomes research, and the value that PCORI offers in funding studies that compare specific treatment options and focus on dissemination and implementation of their findings


PCORI’s Achievements in Health Research and Future Outlook

Dr. Joe Selby, Executive Director, Patient-Centered Outcomes Research Institute (PCORI) presented highlights from PCORI’s comparative clinical effectiveness research (CER) portfolio. Dr. Selby also discussed recently released and upcoming funding announcements and reviewed PCORnet’s achievements and outlook.
View Recording | Download Slides

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