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Achieving a Learning Health System through Collaborative Engagement and the Creation of a Statewide Research Infrastructure and Clinical Data Resources

Project Description: Health Sciences South Carolina (HSSC) is a research collaborative engaging South Carolina’s largest health systems, academic medical centers, and research intensive universities. HSSC’s vision is to establish a statewide learning health system through engaging public and private partners. HSSC is based at University of South Carolina (USC), with its two medical schools, USC School of Medicine (SOM) Columbia and USC SOM Greenville. Additional HSSC supported organizations include Medical University of South Carolina (MUSC), and Clemson University (Clemson), as well as the state’s major health systems: AnMed Health (AH), Greenville Health System (GHS), McLeod Health (MH), Palmetto Health (PH), Self Regional Health System (SelfRHS), and Spartanburg Regional Health System (SRHS). HSSC convenes research and clinical leaders, develops shared clinical data and research resources, and provides statewide training.

In 2013, HSSC unveiled its multi-institutional Clinical Data Warehouse (CDW), which captures and harmonizes historical and near-real time clinical and administrative data from heterogeneous health systems, then aggregates and integrates the data into a structured, usable format. HSSC has implemented solutions to complex research network issues, including an innovative governance system, comprehensive data-sharing, security, and patient privacy management. Another HSSC research infrastructure component is an electronic Institutional Review Board (eIRB), a resource that affords cooperative review for research projects and increases statewide collaboration. The HSSC cooperative engagement model between academic medical centers, research institutions, and non-academic health systems has created the shared vision and infrastructure for a statewide learning health system and serves as a model for the national imperative to improve healthcare quality.

Primary contact: Christine B. Turley, M.D.; Chief Medical Officer; Professor of Clinical Pediatrics
Institution: Health Sciences South Carolina; University of South Carolina School of Medicine

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