Project Title: Investigating the Role of Heme-Induced Complement Activation in SCD Pregnancy
Position: Postdoctoral Researcher
Institution: Emory University
Funding NIH Institution/Center: National Heart Lung and Blood Institute
Grant ID: K99HL175098
Dr. Chambliss was born and raised in Atlanta, Georgia. He is a dual graduate of Morehouse School of Medicine with degrees in Biomedical Sciences (PhD) and Clinical Research (MS) currently conducting mentored research at Emory University School of Medicine as a former fellow of both the Emory T32 Hematology Training Program and the K12 IRACDA Fellowships in Research and Science Teaching (FIRST) Program. This unique combination of fellowships has allowed him to engage in traditional research-intensive training while simultaneously receiving formal instruction in scientific pedagogy through mentored teaching experiences. Dr. Chambliss’ overarching research focus lies in the investigation of cardiovascular mechanisms contributing to acute and chronic organ injury in sickle cell disease (SCD). This is a research focus which has been consistent throughout his pre- and post-doctoral career. His currently proposed project utilizes multiple humanized mouse models to investigate underlying drivers of poor pregnancy outcomes SCD. This research project combines both basic and translational sciences, and successful completion will pave the way for his continued pre-clinical/clinical investigations. In addition to these works, Dr. Chambliss is highly dedicated to developing effective scientific teaching strategies and improving diversity, equity, and inclusion in STEM. This has led him to collaborative efforts with the Atlanta University Center Consortium of HBCUs to develop courses aimed at improving learning outcomes amongst students underrepresented in STEM. Through the continued mentorship provided through the MOSAIC K99/R00 Award and a strong personal dedication, Dr. Chambliss will solidify many of the skills needed to continue his career in science while transitioning to a successful career in independent investigation.