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    Comparative Effectiveness and Outcomes Research

    To make informed care decisions, clinicians and patients need to compare and evaluate various treatment options. Comparative effectiveness research happening at AAMC member institutions supports this decision-making by enhancing the clinical information available about health interventions and care outcomes.   

    Through our work, the AAMC promotes both research and dissemination strategies for studying effective treatments and sharing evidence-based practices. Additionally, the AAMC supports efforts of federal government agencies and other organizations to advance knowledge and engagement in these areas.

    The Latest News

    AAMC Submits Comments about PCORI’s Proposed National Priorities for Health

    The AAMC submitted comments to the Patient-Centered Outcomes Research Institute (PCORI) about the Institute’s Proposed National Priorities for Health. The AAMC supports PCORI’s strategic planning process and the development of these priorities around long-term goals for health. The AAMC feels the five priorities serve as effective pillars on which PCORI can build its Research Agenda. The proprosed National Priorities for Health are:

    • Increase Evidence for Existing Interventions and Emerging Innovations in Health
    • Enhance Infrastructure to Accelerate Patient-Centered Outcomes Research
    • Advance the Science of Dissemination, Implementation, and Health Communication
    • Achieve Health Equity
    • Accelerate Progress toward an Integrated Learning Health System

    Communications and Insights

    More medical research = better patient care
    AAMC Chief Public Policy Officer, Karen Fisher, JD, and Chief Scientific Officer, Ross McKinney Jr., MD, describe the importance of sustained biomedical research investment through the National Institutes of Health (NIH) and continued funding for comparative effectiveness research through the Patient-Centered Outcomes Research Institute (PCORI).

    AAMC Statement on Next PCORI Executive Director, Nakela Cook, MD
    AAMC Chief Scientific Officer, Ross McKinney Jr., MD, issued the following statement congratulating Dr. Cook on her appointment as the new Executive Director of the Patient-Centered Outcomes Research Institute (PCORI).

    How do you know what treatment is right for you . . . or your patients?
    This AAMCNews article, describes the importance of patient-centered outcomes research, and the value that PCORI offers in funding studies that compare specific treatment options and focus on dissemination and implementation of their findings


    Generating Real-World Evidence to Enhance Knowledge during COVID-19

    As the scientific research community responds to COVID-19, there is value in using real-world data and evidence to inform clinical research. The AAMC’s Research on Care Community (ROCC) hosted a webinar featuring Lesley H. Curtis, PhD, Professor and Chair of the Department of Population Health Sciences at Duke University School of Medicine, who discussed the benefits as well as challenges of generating real-world evidence and highlight specific examples related to COVID-19 research.
    View Recording